The Nobel Prize in Physiology or Medicine 2019 was awarded jointly to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza “for their discoveries of how cells sense and adapt to oxygen availability.”
🎟️ The fundamental importance of oxygen has been understood for centuries, but how cells adapt to changes in oxygen levels has long been unknown.
🎟️ This year’s Nobel Prize awarded work reveals the molecular mechanisms that underlie how cells adapt to variations in oxygen supply.
🎟️ Oxygen sensing is central to a large number of diseases. The discoveries made by this year’s Nobel Prize laureates have fundamental importance for physiology and have paved the way for promising new strategies to fight anaemia, cancer and many other diseases.
🎟️ 2019 Medicine Laureates William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza have identified molecular machinery that regulates the activity of genes in response to varying levels of oxygen.
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